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KMID : 0381919960260010067
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Korean Journal of Microscopy
1996 Volume.26 No. 1 p.67 ~ p.77
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Immunoelectron Microscopic Study on the Endocrine Pancreas of the Native Korean Goat
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Lee Jae-Hyun
Hashimoto Yoshiharu
Kon Yasuhiro
Sugimura Makoto
Lee Hyeung-Sik
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Abstract
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Pancreases obtained from native Korean goats were used, and examined by immunoelectron microscopy using several antisera. Five types cells, glucagon (A), insulin (B), somatostatin (D), and pancreatic polypeptide (PP-I and PP-II) cells, were identified in the pancreatic islets. The morphologies of A, B, and D cells corresponded to the typical charateristics described in previous reports on other mammals. Serotonin immunoreactivity was observed in the D cells on the basis of the granular profiles. Two types of PP cells could be distinguished on the basis of the granular profile: the first type was formed by round, homogeneous secretory granules ($220{\sim}400nm$) having a narrow halo between the dense core and limiting membrane, while the other type consisted of cells whose secretory granules ($240{\sim}440\;nm$ in the major axis, $150{\sim}200nm$ in the minor axis) were pleomorphic, having a dense core and a closely fitting limiting membrane. From these results, we suggest that the pancreatic islets of the native Korean goat consist of five types of endocrine cells, A, B, D, PP-I and PP-II cells. Among these, PP-I type cells may correspond to the classical PP of other mammalian pancreases, while PP-II type cells may correspond to the enterochromaffin cells in other species.
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KEYWORD
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Pancreatic islet, Endocrine cell, Immunoelectron microscopy, native Korean goat
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